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New York headquarters

Ludwig Institute for Cancer Research
666 Third Avenue, 28th floor
New York, N.Y. 10017 USA
T: (212) 450 1500
F: (212) 450 1565

Intellectual Property Manager

Zurich office

Ludwig Institute for Cancer Research
Stadelhoferstrasse 22
8001 Zurich, Switzerland
T: (41) (0) 44 267 62 62
F: (41) (0) 44 267 62 00

Brussels Branch

Ludwig Institute for Cancer Research
Avenue Hippocrate 74, Bte B1.74.03
Brussels BRU, 1200
T (32) 2 764 74 59
F (32) 2 762 94 05

Harvard Center

Ludwig Center at Harvard
450 Brookline Avenue
Boston MA, 02215
T 617 632 3985
F 617 632 3408

Johns Hopkins Center

Ludwig Center at Johns Hopkins
1650 Orleans Street, Cancer Research Building, Room 590
Baltimore MD, 21287
T 410 955 8878
F 410 955 0548

Lausanne Branch

Ludwig Institute for Cancer Research
Chemin des Boveresses 155
Épalinges VD, 1066
T (41) 21 314 06 24
F (41) 21 692 59 95
Pre-Clinical Research Associate

Pre-Clinical Research Associate

Ludwig Cancer Research is an international collaborative network of acclaimed scientists that has pioneered cancer research and landmark discovery for more than 40 years. Ludwig combines basic science with the ability to translate its discoveries and conduct clinical trials to accelerate the development of new cancer diagnostics and therapies. Since 1971, Ludwig has invested nearly $2.7 billion in life-changing science through the not-for-profit Ludwig Institute for Cancer Research and the six U.S.-based Ludwig Centers.

Scientists at the Lausanne Branch focus on tumor immunology and immunotherapy. This includes the mechanisms by which tumors thwart immune attack and the development of novel immunotherapies, especially those in which the treatment is tailored to a patient’s cancer—such as dendritic cell vaccines and therapies that involve the manipulation and reinfusion of a patient’s T cells.

The laboratory of Dr. George Coukos at Ludwig Lausanne comprises an international group of highly motivated research associates, post-doctoral fellows, students and technicians. The T-cell engineering team focuses heavily on the development of clinically translatable immunotherapy-based projects, with strong emphasis on protocol development and optimization. There is an on-site GMP facility under construction in Epalinges and a variety of clinical trials under the direction of Dr. Coukos are underway and planned at the CHUV. Thus, this post offers the opportunity to work on exciting projects that have the potential to be translated to the clinic and have an important impact on cancer patients.

The HI-TIDE T-cell engineering team of Dr. Melita Irving in the Coukos laboratory is seeking a Pre-Clinical Research Associate. The position will start as a 1-year contract beginning November 1, 2017, however, candidates interested in a long-term commitment are also encouraged to apply.

The Associate will evaluate various combinatorial cancer immunotherapies (CAR/TCR T-cell transfer, check-point blockade, radiotherapy, chemotherapy, etc.) that have been developed by the team and are of strong interest for clinical translation. The position will involve the screening of novel compounds, but will not include an independent research program. The candidate will work closely with the project leader, post-docs and PhD students, to ensure robust and reproducible in vivo testing. A small group of technicians will provide further support. The candidate will help co-ordinate mice in PyRAT and take a leadership role in writing various reports and authorizations for the lab pertaining to in vivo work.

Tumor models include both syngeneic ones like B16 melanoma in C57BL/6 mice, and human tumors/cell lines engrafted in NSG mice. Tumor control by imaging and/or caliper measurement, tumor microenvironment evaluation pre- and post-treatment, and immune response to therapy will be characterized. Blood, lymph node, tumor and organ extractions will be made. Frequently used in vitro methods will include primary T-cell culture (both human and mouse), microscopy, multi-colour flow cytometry for T-cell phenotyping etc., pPCR etc.

The ideal candidate will possess the following qualifications:

  • PhD or post-doctoral experience in cancer research and immunology.
  • Expertise in T-cell biology and tumor immuno-biology.
  • Extensive hands-on experience with pre-clinical in vivo tumor models and cancer immunotherapy.
  • LTK1 training or equivalent for working with animals in Switzerland. LTK2 certification also desirable but training can be completed upon hiring.
  • Background in T-cell engineering desirable but not required.
  • Strongly motivated, good communication skills and team spirit.
  • Attention to detail, capable of trouble-shooting, working under pressure and meeting deadlines.
  • Fluent spoken and written English is required.

Interested candidates should send a CV, a letter of motivation and contact information for 2-3 references to

M.I.T. Center

Ludwig Center at MIT
77 Massachusetts Avenue, 76-158
Cambridge MA, 02139
T 617 258 5159
F 617 258 5213

MSK center

Ludwig Center at MSK
1275 York Avenue, Box 212
New York NY, 10065
T 646 888 3165
F 646 422 0453

N.Y. Collaborative Laboratory

Ludwig Collaborative Laboratory
MSK, 417 E. 68th Street, Z1525
New York NY, 10065
T 646 888 2315

Oxford Branch

Ludwig Institute for Cancer Research
University of Oxford, Nuffield Department of Clinical Medicine
Old Road Campus Research Building, Headington OXF, OX3 7DQ
T +44 (0)1865 617500
F + 44 (0) 1865 617515

San Diego Branch

Ludwig Institute for Cancer Research
9500 Gilman Drive, Cellular and Molecular Medicine East Building
La Jolla CA, 92093-0670
T 858 534 7802
F 858 534 7750

Stanford Center

Ludwig Center at Stanford
Lokey Stem Cell Research Building - 265 Campus Dr, 3rd Floor
Stanford CA, 94305-5323
T 650 234 0675

Stockholm Branch

Ludwig Institute for Cancer Research
Karolinska Institute, Box 240
Stockholm ST, SE-17177
T (46) 8 524 871 00
F (46) 8 33 28 12

University of Chicago Center

Ludwig Center at the University of Chicago
5758 South Maryland Avenue MC 9006
Chicago IL, 60637
T 773 702 0817
F 773 834 7233

Uppsala Branch

Ludwig Institute for Cancer Research
Box 595
Uppsala UP, 751 24
T (46) 18 16 04 00
F (46) 18 16 04 20