Initially trained as an MD, I began basic research under the guidance of Jacques Van Snick, who just identified IL-6 on the basis of its growth factor activity for plasmacytomas and hybridomas.
My research is focused on the characterization of cytokine activities using a multidisciplinary approach extending from molecular characterization of signal transduction and gene regulation pathways to in vivo studies of inflammatory and immune responses in transgenic and gene-targeted mice. We have a particular interest in the biology of Interleukin-9 (IL-9) and IL-22, two cytokines discovered in our lab.
In addition to my Ludwig research activities, I am a Professor at the University of Louvain Medical School, where I am teaching Immunology and Cell Biology. I am serving on different national and international scientific committees and Editorial boards and I am a member of the Belgian Royal Academy of Medicine.
MD (1988) and PhD (1994), Université catholique de Louvain, Brussels, Belgium
Fellowships: Research Fellow and post-doctoral Fellow with the Fonds de la Recherche Scientifique (FNRS)
Wivine and Jacques Allard-Janssen Award, Belgium, 2012
Pfizer Award, FNRS Belgium, 2008
International InBev-Baillet-Latour Health Prize, 2000
Young Investigator Award, International Cytokine Society, 1999
Maggy and Robert de Hovre Award in Immunology (Fondation Maggy et Robert de Hovre, Brussels, Belgium), 1999
Fernand de Waele Award, FNRS Belgium, 1997