Johan Lennartsson lab

Our work in the PDGF Signal Transduction Section aims to elucidate the molecular mechanism employed in PDGF-induced signal transduction. Cell growth and divisionmust be carefully controlled for an organism to maintain homeostasis, and deregulation of cell proliferation is a common feature of malignant disease. A primary function of growth factors such as PDGF is to transmit signals into the cell that are critical for cell division. Consequently, perturbations of these signals might result in cancer.