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Exploring careers in academia and beyond

This webinar features a panel discussion on potential career paths in academia and beyond with Ludwig alumni and partners who have moved from the lab to industry, government and public health policy: Linda Bauld (Bruce and John Usher Professor of Public Health, Usher Institute, College of Medicine, University of Edinburgh), Adriel Cha (Life Science Consultant, L.E.K Consulting), Michel Detheux (President & CEO, iTeos Therapeutics) and Fiona Reddington (Executive Director of Strategic Partnerships, Early Disease Detection Research Project UK). It was designed with early career scientists in mind.

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The future of cancer research in the “new normal”

This panel discussion with Ludwig Harvard Co-director George Demetri, Ludwig Harvard Investigator Peter Sorger, Ludwig Lausanne Member Johanna Joyce and Ludwig MSK Member Jedd Wolchok, moderated by Rachel Reinhardt, Ludwig’s Senior Vice President for Communications, focuses on how to keep cancer research moving forward in these unprecedented times while ensuring the safety of our teams and patients. The panelists shared how they have pivoted in response to the COVID-19 pandemic, best practices for conducting cancer research in our current environment, and how they are returning, or plan to return, safely to the lab.

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1591920000
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Optimizing remote teams

This webinar features a presentation from Chad Owen, an expert in virtual team facilitation, and insights from Ludwig Stanford’s Ravi Majeti and Ludwig Oxford’s Chunxiao Song. It includes an overview of the virtual convening landscape, as well as a live demonstration of the latest online tools and techniques to optimize team communication.

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Earlier detection of cancer

Ludwig Johns Hopkins Co-director Ken Kinzler gives an overview of his team’s latest work on the early detection of cancer and discusses both the opportunities and challenges of detecting cancer earlier.

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Normalizing the tumor microenvironment to improve immunotherapy of cancer

Ludwig Harvard investigator Rakesh Jain discusses how the abnormal tumor vessels and matrix create a hostile microenvironment that fuels tumor progression and confers resistance to conventional and emerging cancer treatments.

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Utilizing molecular imaging technologies to predict, monitor and optimize immunotherapies

Sam Gambhir, the Virginia and D. K. Ludwig Professor of Cancer Research at Stanford University School of Medicine, gives an overview of molecular imaging technologies and how they are being utilized to monitor immunotherapies in living subjects.

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Strategies to investigate and target the tumor microenvironment

Ludwig Lausanne’s Johanna Joyce introduces the general features of the tumor microenvironment; discusses critical functions of tumor-promoting myeloid cells in regulating cancer progression, metastasis and therapeutic resistance; and outlines current strategies for therapeutic targeting.

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1539907200
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Clinical research in an era of disease-agnostic basket trials

Ludwig Harvard Director George Demetri discusses the next generation of pathway-targeting therapies being tested against many cancer types and how clinical trials can be designed to optimize collaboration between lab-based researchers and clinical scientists, generating new insights into cancer sensitivity and resistance to therapy.

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1508371200
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Convergence of the circadian clock and cancer

Ludwig Scientific Director Chi Van Dang has worked to unravel how the oncogene MYC links the aberrant metabolism of cancer cells to their unchecked proliferation.

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1507593600
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Scale and complexity of hypoxia signaling pathways and their implications for cancer

Ludwig Oxford’s Peter Ratcliffe outlines the HIF hydroxylase pathway, discusses its evolution and considers its operation in health and disease.

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1476921600
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The circuitry of metastasis

Ludwig MIT Director Robert Weinberg discusses his laboratory’s extensive investigation of a complex cell-biological program known as the epithelial-mesenchymal transition (EMT). In carcinomas, EMT results in the acquisition of multiple traits associated with high-grade malignancies.

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1476835200
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Precision medicine: What is missing from the current initiatives?

Ludwig San Diego’s Bing Ren provides an overview of current large-scale efforts to uncover functional elements of the human genome using new technologies.

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Pharmacogenomics

Ludwig Oxford alum Sebastian Nijman discusses his development of isogenic—or genetically uniform—cell lines to study how drugs interact with the variegated genetic landscape of malignant tumors, and their application to analyze drug resistance and identify surprising candidate drug targets major cancers.

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Immunomodulation of the tumor microenvironment

Ludwig’s Benoît Van den Eynde tells the story of this discovery and its subsequent translation to develop a pair of candidate immunotherapies, one of which will soon enter clinical trials in partnership with Pfizer.

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1442966400
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Pathways to Carcinogenesis: Stem cells, progression and the rogue cell’s ‘Don’t eat me’ signal​​

Ludwig Stanford Director Irv Weissman covers his laboratory’s investigation of cancer stem cells with an emphasis on CD47.

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1426636800
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Unraveling glioblastoma’s resistance

Web Cavenee (a cancer geneticist), Frank Furnari (a cancer biologist) and Paul Mischel (a cancer pathologist) of Ludwig San Diego describe their joint investigation of glioblastoma over the past several years.

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Strategies for winning the wars on cancer

Ludwig Johns Hopkins Co-director Bert Vogelstein speaks about what the past four decades of research has taught us about the mechanics of cancer, what genomics and molecular biology have taught us about it and how all of this information might best be exploited to address the challenges posed by cancer.

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1393372800
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Genome-wide transcriptomic analyses of single cells

Webinar by Ludwig alum Rickard Sandberg. The comprehensive capture of all RNA species present inside a single cell has been a long-standing goal of biology.

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Therapeutically exploiting cytokines that link inflammation to tumor progression

Ludwig Melbourne alum Matthias Ernst speaks about his research on therapeutically exploiting cytokines that link inflammation to tumor progression, including insights he has gained from mouse models used to mimic gastrointestinal tumorigenesis in the presence and absence of chronic inflammation, and the potential for interleukin-11 signaling as a therapeutic target.

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