Check out the very first edition of the Image gallery, a selection of striking and informative micrographs shared with us by researchers from across the Ludwig community. The image above, submitted by Ludwig Lausanne’s Ping-Chih Ho and Stefania Vilbois, captures a mouse melanoma ten days post-engraftment, showing CD8+ tumor-infiltrating lymphocytes (orange and red), dendritic cells (green), blood vessels (Qdot, gray), and collagen fibers (second harmonic generation, cyan).
Read MoreResearchers led by Ludwig Stanford’s Michelle Monje and Crystal Mackall reported in Nature remarkably encouraging final results for one arm of an ongoing Phase 1 trial evaluating CAR-T cell therapy directed against the ganglioside GD2 for the treatment of H3K27M-mutated diffuse midline gliomas, a family of aggressive and incurable pediatric brain cancers.
About 15 years ago, researchers at Ludwig Johns Hopkins and their colleagues at the former Ludwig Melbourne Branch began a collaboration to determine whether circulating tumor DNA could consistently predict disease recurrence after surgery for stage II colon cancer—and do so well enough to safely spare patients unnecessary chemotherapy following surgery. Their analysis of mature outcome data, reported in Nature Medicine, confirmed the answer is a resounding “yes!”
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