Helen Byrne
Tumor biology, Tumor microenvironment


BA/MA, Mathematics, University of Cambridge, UK, 1987

MSC, Mathematical Modelling and Numerical Analysis, University of Oxford, UK, 1988

PhD, Modelling combustion zones in porous media, University of Oxford, UK, 1991

My research focuses on the development and analysis of mathematical and computational models that describe biomedical systems, with particular application to cancer and its treatment. My aims in studying such models are two-fold: to identify the mechanisms responsible for observed biomedical phenomena and to abstract novel features from the resulting mathematical models that merit theoretical investigation. More recently, my research interests have broadened to include the development of statistical and mathematical approaches for analyzing complex, high-dimensional datasets, especially datasets relating to cancer. In the future, I aim to extend these approaches while also developing innovative ways to combine them with complex, multiscale biomedical datasets to progress understanding of disease initiation and progression and, in the longer term, to provide an objective and rational basis to support decision-making in the treatment of cancer and other diseases, including atherosclerosis.

I have undertaken my research at the University of Oxford’s Mathematical Institute (Wolfson Centre for Mathematical Biology) since 2011, and I became a senior group leader at the Ludwig Institute for Cancer Research Oxford Branch in 2022.

In 2019, I received the Leah Edelstein-Keshet Award from the Society for Mathematical Biology in recognition of my scientific achievements coupled with active leadership in mentoring scientific careers. In 2020 I became a Fellow of the Society for Mathematical Biology.


Ludwig Institute for Cancer Research, Oxford
Nuffield Department of Clinical Medicine
Old Road Campus Research Building
off Roosevelt Drive, Headington, Oxford, OX3 7DQ, UK

T +44 (0) 1865 617507


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