Oxford

The Oxford Branch studies signaling pathways that influence cancer initiation and progression, with a focus on infection, inflammation and cancer epigenetics. We aim to advance cancer prevention, early diagnosis and effective treatment.

About

Ludwig Oxford approaches the problems of cancer biology from several different angles. Our research program explores cancer susceptibility, initiation, progression, metastasis and resistance to therapy, and includes technical expertise essential to the development of novel clinical and research technologies—such as computational modeling and chemical biology. Over all, our specific areas of interest include the study of tumor heterogeneity and the regulation of gene expression, reflecting our interests in genetics, epigenetics, the tumor microenvironment, cell signaling and gene expression. Our branch has recently launched a multidisciplinary research program focused on upper gastrointestinal cancers, with the aim of developing novel approaches to preventing, diagnosing and treating such malignancies. Our laboratories are housed in the Old Road Campus Research Building, and we are affiliated with the Nuffield Department of Medicine at the University of Oxford.

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Adjuncts

Highlights

News

August 12, 2019
January 8, 2019
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Careers

Group Leader – Cancer Epigenetics
Deadline: November 23, 2020
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Nuffield Department of Medicine (NDM), Ludwig Institute for Cancer Research and Oxford Big Data Institute, Old Road Campus Research Building, Roosevelt Drive, Headington, Oxford, UK.

Grade 10: £55,750 – £64,605 p.a. (with a discretionary range from £66,539 – £70,579 p.a.). Depending on experience, this role may be offered at Grade 9: £48,114 – £55,750 per annum with reduced responsibilities.

Only online applications received by 12:00 PM (noon, UK time), November 23, 2020, will be considered.

The Ludwig Institute for Cancer Research, Oxford Branch, is recruiting a Group Leader with research interests in cancer epigenetics or cancer and infection. We encourage applications from researchers with a background in epigenetics in the immune system and interactions with metabolism in the context of cancer biology. Potential connections to translational medicine would be of particular interest.

As a Group Leader, the successful candidate will initiate and implement long-term, often interdisciplinary research programs in cancer epigenetics or cancer and infection, develop now areas of research for publication in high-impact journals and collaborate with other scientists to achieve research aims. He or she will be responsible for the management and monitoring of substantial research resources and budgets, and will be expected to generate research income, actively promote the research area, write funding applications for new projects and play a key role in establishing overall research strategy. The successful applicant will also be expected to provide effective people management by motivating, supervising and communicating with all members of the team and to supervise research students, ensuring intellectual stimulus and access to resources necessary for a successful period of study at the Institute.

Applicants must have a relevant PhD/DPhil degree with significant post-qualification research experience, including experience in leading successful and novel research programs. They are expected to have an international reputation in their field of expertise and a specialist knowledge in cancer epigenetics or cancer and infection. They should also have an established international publication record and show evidence of a successful track record in attracting funding and managing budgets. An appointment at grade 9 will be considered for applicants with less experience who have the appropriate research profile.

The Ludwig Institute for Cancer Research will provide significant resources, including core funded posts and consumables/equipment budgets. This post is offered full-time on a 5-year fixed term contract funded by the Ludwig Core Award.

Applications must be made online by 12.00 noon (UK time) on  November 23, 2020.

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Postdoctoral Researcher in Methyltransferases
Deadline: December 16, 2020
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Postdoctoral Researcher in Methyltransferases

Nuffield Department of Medicine (NDM), Ludwig Institute for Cancer Research and Oxford Big Data Institute, Old Road Campus Research Building, Roosevelt Drive, Headington, Oxford, UK.

Grade 7: Salary in range £32,817 – £40,322 per annum

Only online applications received by 12:00 noon (UK time), December 16, 2020, will be considered.

The Ludwig Institute for Cancer Research, Oxford Branch, is seeking a Postdoctoral Research Scientist in Methyltransferases to join Professor Yang Shi’s research group to investigate newly identified RNA m6A methyltransferases. This is an exciting opportunity to join a leading cancer research institute.

As Postdoctoral Research Scientist in Methyltransferases, you will investigate newly identified RNA m6A methyltransferases using biochemical, molecular and genetic approaches to study their functions and mechanisms of action in both cell lines and model organisms. You will manage your own academic research and administrative activities, including small-scale project management, and coordinate multiple aspects of work to meet deadlines. You will use your expertise to supervise and train junior staff in chromatin and cancer biology. You will interpret results and present them to senior members of the group and Professor Shi. You will communicate with Professor Shi and other members of the group as required, ensuring that they are kept fully up to date with progress and any difficulties in the research project. You will work towards publishing your findings in international journals and representing the group at meetings.

Applicants must have a PhD in a relevant field and previous laboratory experience relevant to the project, as well as significant background in RNA biochemistry. The successful candidate will have a strong publication record for career stage, such as first-author publications in internationally recognized journals, a demonstrated attention to detail and excellent written and verbal communication skills.

This post is fixed term for 3 years and is funded by the Ludwig Institute for Cancer Research.

Applications must be made online by 12:00 noon (UK time), December 16, 2020.

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   Back to Locations

Ludwig Institute for Cancer Research, Oxford
Nuffield Department of Clinical Medicine
Old Road Campus Research Building
off Roosevelt Drive, Headington, Oxford, OX3 7DQ, UK

T +44 (0) 1865 617507

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