Oxford

The Oxford Branch studies signaling pathways that influence cancer initiation and progression, with a focus on infection, inflammation and cancer epigenetics. We aim to advance cancer prevention, early diagnosis and effective treatment.

About

Ludwig Oxford approaches the problems of cancer biology from several different angles. Our research program explores cancer susceptibility, initiation, progression, metastasis and resistance to therapy, and includes technical expertise essential to the development of novel clinical and research technologies—such as computational modeling and chemical biology. Over all, our specific areas of interest include the study of tumor heterogeneity and the regulation of gene expression, reflecting our interests in genetics, epigenetics, the tumor microenvironment, cell signaling and gene expression. Our branch has recently launched a multidisciplinary research program focused on upper gastrointestinal cancers, with the aim of developing novel approaches to preventing, diagnosing and treating such malignancies. Our laboratories are housed in the Old Road Campus Research Building, and we are affiliated with the Nuffield Department of Medicine at the University of Oxford.

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Adjuncts

Highlights

News

August 12, 2019
January 8, 2019
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Careers

Postdoctoral Research Scientist—Epigenetic Mechanisms
Deadline: January 2, 2020
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Ludwig Cancer Research is an international collaborative network of acclaimed scientists that has pioneered cancer research and landmark discovery for more than 40 years. Ludwig combines basic science with the ability to translate its discoveries and conduct clinical trials to accelerate the development of new cancer diagnostics and therapies. Since 1971, Ludwig has invested nearly $2.7 billion in life-changing science through the not-for-profit Ludwig Institute for Cancer Research and the six U.S.-based Ludwig Centers.

Scientists at the Oxford Branch of the Ludwig Institute for Cancer Research focus on a variety of subjects of importance to cancer research. These range from intracellular signaling, genomics and epigenetics to tumor immunology, oxygen sensing and angiogenesis. With stable core funding from Ludwig Cancer Research and access to state-of-the-art facilities in the renowned academic environment of the University of Oxford at the Old Road Research Campus, our PIs have both the opportunity and means to pursue groundbreaking basic and translational scientific research.

Postdoctoral Research Scientist—Epigenetic Mechanisms

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 Nuffield Department of Medicine (NDM), Ludwig Institute for Cancer Research and Oxford Big Data Institute, Old Road Campus Research Building, Roosevelt Drive, Headington, Oxford, UK.

Grade 7: £32,817- £40,322 p.a.

Only online applications received by 12:00 PM (noon, UK time), January 2nd, 2020, will be considered.

The Ludwig Institute for Cancer Research, Oxford Branch, seeks a Postdoctoral Research Scientist to study epigenetic mechanisms in cancer. The project will apply recently developed state-of-the-art DNA methylation sequencing technologies to analyze patient samples from a unique experimental medicine clinical trial of immunotherapy in esophageal cancer, with the aim of uncovering epigenetic mechanisms in tumor biology and responses to cancer therapy. The position is based in the labs of Prof Xin Lu and Dr Chunxiao Song.

The candidate must have or be close to completing a PhD in molecular biology, biochemistry, genetics, chemistry or related science degree. Experience in NGS techniques and skills in molecular biology techniques are essential.

More information about the position and its responsibilities is available by pressing the “Job Description” button here.

Applications must be made online by 12:00 PM (noon, UK time), January 2nd, 2020.

See Full Job Posting    

Postdoctoral Research Scientist – Chemical Epigenetics
Deadline: January 13, 2020
See More

Ludwig Cancer Research is an international collaborative network of acclaimed scientists that has pioneered cancer research and landmark discovery for more than 40 years. Ludwig combines basic science with the ability to translate its discoveries and conduct clinical trials to accelerate the development of new cancer diagnostics and therapies. Since 1971, Ludwig has invested nearly $2.7 billion in life-changing science through the not-for-profit Ludwig Institute for Cancer Research and the six U.S.-based Ludwig Centers.

Scientists at the Oxford Branch of the Ludwig Institute for Cancer Research focus on a variety of subjects of importance to cancer research. These range from intracellular signaling, genomics and epigenetics to tumor immunology, oxygen sensing and angiogenesis. With stable core funding from Ludwig Cancer Research and access to state-of-the-art facilities in the renowned academic environment of the University of Oxford at the Old Road Research Campus, our PIs have both the opportunity and means to pursue groundbreaking basic and translational scientific research.

_________________________________________________________________________________________________________________________________

Postdoctoral Research Scientist – Chemical Epigenetics

Nuffield Department of Medicine (NDM), Ludwig Institute for Cancer Research and Oxford Big Data Institute, Old Road Campus Research Building, Roosevelt Drive, Headington, Oxford, UK.

Grade 7: £32,817- £40,322 p.a.

Only online applications received by 12:00 PM (noon, UK time), January 13, 2020, will be considered.

The Ludwig Institute for Cancer Research, Oxford Branch, seeks a postdoctoral research scientist specializing in chemical epigenetics. The position is based in the lab of Chunxiao Song. The group combines various chemical biology and genome technologies to develop novel tools to analyse the epigenome, including the recently developed bisulphite-free method for sequencing DNA methylation called TAPS.

The successful candidate will participate in a research programme led by Chunxiao Song to further develop TAPS technology for epigenetic sequencing of circulating cell-free DNA, long-read epigenetic sequencing and single-cell epigenetic sequencing. The researcher will also develop new chemistry in epigenetics and epitranscriptomics.

The applicant must have a PhD or be close to receiving one in chemistry/molecular biology/biochemistry/genetics or have a related science degree. Experience in next generation sequencing and a strong skill set in chemical biology/molecular biology/biochemistry techniques is essential.

More information about the position and its responsibilities can be accessed by pressing the “Job Description” button here.

Applications must be made online by 12.00 noon (GMT) on January 13, 2020.

See Full Job Posting    

   Back to Locations

Ludwig Institute for Cancer Research, Oxford
Nuffield Department of Clinical Medicine
Old Road Campus Research Building
off Roosevelt Drive, Headington, Oxford, OX3 7DQ, UK

T +44 (0) 1865 617507

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