Roughly half of cancer cases stem from preventable causes and many more could likely be prevented if the science of cancer prevention got more attention and material support than it has traditionally. Several Ludwig researchers are training their sights on cancer prevention and on improving the detection of cancer, which can often be cured if it is caught early. These are major aims of a research program we’ve launched in partnership with the Conrad N. Hilton Foundation on the diet-based prevention and early, non-invasive detection of gastrointestinal cancers. Ludwig researchers are also working, with the same goal, on esophageal and gastric cancers and the estimation of risk for colon cancer. These and other Ludwig research efforts bring together subdisciplines of cancer research ranging from tumor immunology to cancer genomics and seek to translate basic scientific discoveries into novel diagnostics and scientifically rigorous preventive interventions.
Ludwig Johns Hopkins Co-director Ken Kinzler gives an overview of his team’s latest work on the early detection of cancer and discusses both the opportunities and challenges of detecting cancer earlier.
Ludwig Johns Hopkins Co-director Bert Vogelstein speaks about what the past four decades of research has taught us about the mechanics of cancer, what genomics and molecular biology have taught us about it and how all of this information might best be exploited to address the challenges posed by cancer.