Roughly half of cancer cases stem from preventable causes and many more could likely be prevented if the science of cancer prevention got more attention and material support than it has traditionally. Several Ludwig researchers are training their sights on cancer prevention and on improving the detection of cancer, which can often be cured if it is caught early. These are major aims of a research program we’ve launched in partnership with the Conrad N. Hilton Foundation on the diet-based prevention and early, non-invasive detection of gastrointestinal cancers. Ludwig researchers are also working, with the same goal, on esophageal and gastric cancers and the estimation of risk for colon cancer. These and other Ludwig research efforts bring together subdisciplines of cancer research ranging from tumor immunology to cancer genomics and seek to translate basic scientific discoveries into novel diagnostics and scientifically rigorous preventive interventions.