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Welcome letter



Ludwig Oxford’s Yang Shi elected to the U.K. Academy of Medical Sciences

Ludwig Lausanne’s Douglas Hanahan elected Foreign Member of the Royal Society



A new Leadership Fellow at Ludwig Oxford

Ludwig Princeton’s first faculty hire



Michael Waterfield, 1941-2023



Ludwig Oxford labs earned a Silver rating for sustainability



A chemical modification makes MITF switch genomic targets

A searching analysis of TANs yields clues to improving brain tumor therapy

A duo of personalized therapies take on advanced ovarian cancer

A simple metabolic tweak usefully transforms T cell identity

How T cell exhaustion differs between cancer and chronic viral infection

How oncogenic MYC disrupts the molecular clock— and much more—in cells

A high-res protein structure yields a blueprint for precision drug design

Functional analysis suggests new approach to treating subset of myeloproliferative neoplasms

Co-targeting a cancer cell dependency may boost the efficacy of KRAS inhibitors

A targeted nanoparticle delivers a one-two punch to tumors

In the works: a better way to detect brain cancers

Tracing the sources of cell-free DNA

How a neurotransmitter helps initiate melanoma

The KRAS oncogene generates a stem cell to spawn an indolent lung cancer

Gene expression is surprisingly coordinated across the tumor microenvironment

Molecular markers predict outcomes for patients with liver metastases of colorectal cancer

A novel mechanism for evolution of drug resistance in lung cancers

Tumor monocytes take a star turn in immunochemotherapy for esophageal cancer

Bridging the parallel worlds of multiplex imaging and H&E microscopy

Common blood pressure drugs stimulate anti-tumor immune responses

Why neoantigen-specific T cells are better at targeting tumors

Functional genomics approach finds scores of drug targets for multiple myeloma

Not just a fuel for growth: Estrogen drives oncogene amplifications in breast cancer

Blocking an RNA-targeting protein could enhance responses to radiotherapy

Precursor cells of a rare leukemia tour the body to become malignant

A cellular sensor of reactive oxygen species and its role in drug resistance

Potently anti-tumor T cells gather in subset of lung-to-brain metastases

A way to model virtually any mutation associated with cancer

Cells of the tumor microenvironment compensate for the loss of Tregs

Lung tumors that are poorly infiltrated with effector T cells express better antigens

Two technologies at the cutting edge of T cell engineering

A DNA-barcoded nanotech for the detection, identification and staging of cancer

A polymorphism in a promoter explains a mystery of the blood



Ludwig Oxford’s Richard White models cancer in fish that are easy to manipulate genetically and enable the clear visualization of individual cancer cells as they spread.



Given the influence public opinion has on science funding and policy decisions, what can we—as individuals and as a community—do to build public support for scientific research?


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