The Ludwig Center at MIT is focused on the processes associated with malignant progression, specifically on the mechanisms that allow cancer cells originating in primary tumors to disseminate and ultimately form metastatic colonies.
Cancer progression is a multi-step process that involves a series of cell-biological and biochemical changes in malignant cells. We investigate that process at several levels, exploring the changes within cells that permit its migration all the way through to the biological determinants that permit disseminated cancer cells to gain a foothold in foreign tissues, where they can spawn metastatic colonies.
The Ludwig Center for Molecular Oncology is housed within the David H. Koch Institute for Integrative Cancer Research at the Massachusetts Institute of Technology.
Ludwig Center at MIT
77 Massachusetts Avenue, 76-158
Cambridge, Massachusetts, U.S. 02139
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