Princeton

The Princeton Branch focuses on cancer metabolism—its roles in tumor growth and metastasis, its connections to the microbiome and immune system and its manipulation by diet and drugs—all with the aim of improving the prevention, diagnosis and treatment of cancer.

About

The Ludwig Princeton Branch is dedicated to the investigation of cancer metabolism and the development of novel metabolic interventions for the prevention, diagnosis and treatment of malignancies. Our researchers explore crosstalk between the microbiome, major body organs, immune cells and tumors; metabolic rewiring in cancer metastasis; and mechanisms by which advanced cancers promote cachexia, the severe loss of body mass that often contributes to cancer mortality. We also investigate the influence of diet on cancer metabolism, including how diet affects the tumor microenvironment, anti-cancer immune response, cancer risk, disease progression and patient responses to therapy. The Branch is located at Princeton University and affiliated with RWJBarnabas Health and Rutgers Cancer Institute of New Jersey.

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Careers

Application for Ludwig Princeton Scholar
Deadline: September 21, 2021
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Princeton University is pleased to announce a search for Ludwig Princeton Scholars, a new program aimed at attracting talented early-career scientists (0-2 years from PhD, MD, or clinical training). The program centers on cancer metabolism, broadly defined to include technology development, computation, biological studies, drug development, and clinical trials relevant to diet, metabolism, cancer, cell growth, metastasis, autophagy, microbiome, and/or the immune system. Scholars will be housed at the new Ludwig Princeton Branch on Princeton University’s campus, or in collaborating labs at the Cancer Institute of New Jersey. Appropriate backgrounds include a Ph.D. in biology, chemistry, computer science, engineering, physics or an M.D. Appointment will be as Associate Research Scholar, renewable for up to five years, with a competitive salary and research support.

Scholars will be given a substantial degree of independence, with mentorship from at least 2 faculty members, one of whom must be a full member of the Ludwig Princeton Branch (currently, these are Yibin Kang, Josh Rabinowitz, and Eileen White).

Scholars may have the opportunity to perform a modest amount of teaching, according to a plan they may develop in conjunction with their mentors. While teaching, a Scholar may hold a secondary appointment as a Lecturer in an appropriate department, pending sufficient course enrollments and the approval of the Dean of the Faculty.

Submission of all application materials is highly encouraged by September 1, 2021. Scholars will be appointed on a rolling basis. Please feel free to contact Panina Zaurov (pzaurov@princeton.edu) with any inquiries about the Ludwig Princeton Scholars Program. To apply online, please visit https://www.princeton.edu/acad-positions/position/20701 and submit a cover letter, curriculum vitae which includes a list of publications, a brief statement (1-2 pages) of research interests and goals, and contact information for three references.

These positions are subject to the University’s background check policy.

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Application for Ludwig Postdoctoral Research Associate – Princeton
Deadline: September 1, 2021
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Postdoctoral or more senior research positions are available in the Ludwig Princeton Branch to study metabolism and tumor-microenvironment interactions during cancer progression. Ludwig Princeton Branch is dedicated to accelerating the study of metabolic phenomena associated with cancer to develop new paradigms for cancer prevention and treatment. Its main research areas include:

– Metabolic interactions between the tumor and the rest of the body, focusing on how the body supports tumor growth and metastasis, and how tumors induce cachexia and other microenvironmental changes.
– Interplay between host metabolism, gut microbiome, and anti-cancer immune response.
– Diet-induced tumor microenvironment changes during cancer progression and metastasis, and dietary strategies for the prevention and treatment of cancer.

We welcome highly motivated candidates who have or expect to have a Ph.D. degree in the fields of molecular cell biology, cancer biology, chemical biology, biochemistry, cancer genomics, genetics, mass spectrometry, physical chemistry, computational and systems analysis.

Appointments are for one year with the possibility of renewal pending satisfactory performance and continued funding.

Applicants must select one or more research mentor/co-mentor from the following Principal Investigators and Ludwig Princeton Branch members.

Kang, Yibin https://molbio.princeton.edu/people/yibin-kang
Major areas of interest include: Cellular plasticity in cancer progression, organ-tropic metastasis niches, metabolic adaptation during cancer metastasis, metastasis genes and development of metastasis therapeutics, mammary gland stem cell and stem cell niches.

Rabinowitz, Joshua https://scholar.princeton.edu/rabinowitz/home
Major areas of interest include: Metabolomics, isotope tracing, metabolic flux analysis, quantitative modeling, mass spectrometry imaging, cancer metabolism, small molecule inhibitor discovery, dietary impact on cancer, metabolism, and the immune system.

White, Eileen https://www.cinj.org/research/eileen-white-phd
Major areas of interest include: Identification of metabolic vulnerabilities in cancer, the role of nutrient scavenging pathways including autophagy in cancer and host metabolism, growth and survival, metabolic control of the anti-tumor immune response, identification of the mechanisms driving cancer cachexia, dietary modulation of tumor growth and treatment response.

To apply online, please visit https://www.princeton.edu/acad-positions/position/20721 and submit a brief statement of research interests, curriculum vitae and a list of three references.

This position is subject to the University’s background check policy.

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Ludwig Institute for Cancer Research, Princeton
Princeton University
91 Prospect Avenue, 2nd Floor
Princeton, N.J. 08540

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