At every step of the research process from the lab to the clinic, we are pursuing innovative ways to prevent and control cancer.
Researchers led by CEO and Scientific Director of the Ludwig Institute for Cancer Research Chi Van Dang and Maimon Hubbi, a postdoc in his laboratory at Johns Hopkins University, detail the mechanisms by which two defining features of the pancreatic tumor microenvironment—the composition of metabolites in the fluid around the cancer cells and severe oxygen deficiency in the tumors—converge to counter a type of cell death called ferroptosis, suggesting new strategies for the treatment of advanced pancreatic cancer.
Learn in this brief history about the creation of the Ludwig Institute, the establishment of the Ludwig Centers, how they work together to solve the puzzle of cancer—and the enigmatic, endlessly creative shipping titan who bequeathed his sprawling conglomerate to the whole endeavor.